  {"id":198536,"date":"2024-05-29T14:35:12","date_gmt":"2024-05-30T00:35:12","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=198536"},"modified":"2024-05-29T14:35:12","modified_gmt":"2024-05-30T00:35:12","slug":"grant-renewal-diabetes-research","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2024\/05\/29\/grant-renewal-diabetes-research\/","title":{"rendered":"$11.7M grant renewal advances diabetes research in Hawai\u02bbi"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> 2<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span><figure id=\"attachment_198546\" aria-describedby=\"caption-attachment-198546\" style=\"width: 676px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2024\/05\/manoa-gerschenson-le-saux-mau-1.jpg\" alt=\"three people standing in front of medical school \" width=\"676\" height=\"381\" class=\"size-full wp-image-198546\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2024\/05\/manoa-gerschenson-le-saux-mau-1.jpg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2024\/05\/manoa-gerschenson-le-saux-mau-1-300x169.jpg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2024\/05\/manoa-gerschenson-le-saux-mau-1-130x73.jpg 130w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><figcaption id=\"caption-attachment-198546\" class=\"wp-caption-text\">Mariana Gerschenson, Oliver Le Saux and Marjorie Mau with <abbr>JABSOM<\/abbr>&#8216;s Diabetes Research Center<\/figcaption><\/figure>\n<p>Diabetes affects 10&#37; of <span aria-label=\"Hawaii\">Hawai&#699;i<\/span>&#8216;s population, with another 37&#37; living with pre-diabetes, according to the American Diabetes Association. To address this significant health issue, the University of <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> at M\u0101noa\u2019s <a href=\"http:\/\/jabsom.hawaii.edu\">John A. Burns School of Medicine<\/a> (<abbr>JABSOM<\/abbr>) secured a $11.7 million National Institutes of Health (<abbr>NIH<\/abbr>) five-year grant renewal for its Diabetes Research Center, originally funded with $11.3 million in 2017.<\/p>\n<p>&ldquo;Living in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span>, many of us have diabetes or know someone who has it, so it is our obligation as researchers in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> to investigate problems that affect the people of this state,&rdquo; said Mariana Gerschenson, <abbr>JABSOM<\/abbr> associate dean for research and director of the Diabetes Research Center. &ldquo;The renewal of this grant allows us to continue to do this critical research, and we are excited about starting Phase 2 of this research, which will explore the impact diabetes has on other parts of the body.&rdquo; <\/p>\n<p><span class=\"blocklink\">Related story:<a href=\"https:\/\/www.hawaii.edu\/news\/2019\/01\/21\/environmental-microbiomes-human-health-link-grant\/\">$10.4M to <abbr title=\"东精影业\">东精影业<\/abbr> researchers links environmental microbiomes to human health<\/a><\/span><\/p>\n<p>Originally, the <abbr>NIH<\/abbr>-funded Centers of Biomedical Research Excellence (<abbr>COBRE<\/abbr>) grant enabled <abbr>JABSOM<\/abbr> to study the mechanisms behind diabetes and pre-diabetes using cell and animal models. This initiative also facilitated the training of five young investigators across <abbr>东精影业<\/abbr> M\u0101noa to continue to contribute to local research and education.<\/p>\n<p>&ldquo;This is a very exciting time for us to have the opportunity to give young people in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> an opportunity to study this abundant disease and its complications here at home,&rdquo; said Majorie Mau, the center&#8217;s deputy director and professor in the Department of Native Hawaiian Health.<\/p>\n<h2>Impact on local community<\/h2>\n<figure id=\"attachment_138095\" aria-describedby=\"caption-attachment-138095\" style=\"width: 214px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2021\/03\/jabsom-cobre-diabetes-214x300.jpg\" alt=\"woman in lab\" width=\"214\" height=\"300\" class=\"size-medium wp-image-138095\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2021\/03\/jabsom-cobre-diabetes-214x300.jpg 214w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2021\/03\/jabsom-cobre-diabetes-93x130.jpg 93w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2021\/03\/jabsom-cobre-diabetes.jpg 250w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><figcaption id=\"caption-attachment-138095\" class=\"wp-caption-text\">Mariana Gerschenson in the lab.<\/figcaption><\/figure>\n<p>The next research phase will focus on how diabetes leads to complications such as stroke, heart disease and kidney issues, with a special emphasis on Native Hawaiian and Pacific Islander populations, which are disproportionately affected by diabetes.<\/p>\n<p>Gerschenson&#8217;s team includes <abbr>JABSOM<\/abbr> assistant professors Kathryn Schunke, who is researching diabetic cardiomyopathy; Stacy Brown, who studies the genetics of diabetes and stroke among Native Hawaiians and Pacific Islanders; and Noemi Polgar, who investigates glucose transport in skeletal muscle. Additionally, Tyler Ray, assistant professor from <abbr>东精影业<\/abbr> M\u0101noa\u2019s <a href=\"http:\/\/www.eng.hawaii.edu\">College of Engineering<\/a>, is <a href=\"https:\/\/www.hawaii.edu\/news\/2023\/05\/03\/sweatainer-health-device\/\">developing wearable technology to monitor kidney function<\/a>.<\/p>\n<p>The renewal of the grant not only supports ongoing research but also boosts <span aria-label=\"Hawaii\">Hawai&#699;i<\/span>\u2019s economy. According to the <a href=\"https:\/\/www.hawaii.edu\/news\/2024\/04\/10\/uh-biomed-research-fy23-nih-funds\/\">United for Medical Research report<\/a>, every dollar received in grants adds $2.46 in new economic activity. The funding supports the recruitment and development of new faculty and young investigators, ensuring the continuation of innovative diabetes research and education at <abbr>JABSOM<\/abbr> and across <abbr>东精影业<\/abbr>.<\/p>\n<p><a href=\"https:\/\/jabsom.hawaii.edu\/news-events\/news\/2024\/05\/cobre-diabetes-renewed.html\">Read more on <abbr>JABSOM<\/abbr><\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><abbr>JABSOM<\/abbr>\u2019s Diabetes Research Center will use the grant renewal to continue critical research.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[1040,179,31,1467,1363,9],"class_list":["post-198536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-biomedical-science","tag-college-of-engineering","tag-john-a-burns-school-of-medicine","tag-manoa-excellence-in-research","tag-manoa-research","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/198536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/comments?post=198536"}],"version-history":[{"count":7,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/198536\/revisions"}],"predecessor-version":[{"id":198565,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/198536\/revisions\/198565"}],"wp:attachment":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/media?parent=198536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/categories?post=198536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/tags?post=198536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}